Opened 8 years ago

Closed 11 months ago

#161 closed enhancement (wontfix)


Reported by: Susan Owned by: Christof Gessner
Priority: minor Milestone:
Component: help Keywords:


Please add the UOM AI for Avidity Index to the UCUM standard for the autoimmune antibody testing (LUPUS) Ribosomal P SM RNP SSA/SSB SCL-70 Thyroid Peroxidase A

Change History (6)

comment:1 Changed 8 years ago by Gunther Schadow

Would you have a literature reference? I have Googled and can not find the unit "Activity Index" described.

comment:2 Changed 8 years ago by Gunther Schadow

I have verified your user account, so from now on you can comment directly on the tickets.

Thanks for your reply. You wrote:

Quest Diagnostics reports AI (avidity index) on their autoimmune antibody test which uses Immunoassay. It can also be called Affinity Index as I've seen these two terms used interchangeably.

The literature can be found here:

comment:3 Changed 8 years ago by Gunther Schadow

Aha, first I have misread, "avidity". Sorry for that mistake.

So, now we just need to find a crisp definition of the Avidity Index as a unit. Particularly, can you speak about how much avidity index values are comparable between the Abbott assay and another company's assay? Or is it an Abbott specific measure?

Also, would you consider whether AI is not really a unit at all. AI is an index, an observation. You need a LOINC code for it for sure (is there one?) And once you have a LOINC code, why do you need a unit?

comment:4 Changed 13 months ago by Brenée Mitchell

Component: help
Owner: set to Christof Gessner
Status: newassigned

comment:5 Changed 12 months ago by Christof Gessner


There are a number of LOINC codes that measure "avidity" as a ratio. One example is: 81119-0 Also there are a number of Lupus-related tests.

Please transfer to the LOINC committe in charge.

comment:6 Changed 11 months ago by Brenée Mitchell

Resolution: wontfix
Status: assignedclosed

Decision from 17 February 2021 Board meeting:

Reject - Not a UCUM code request, it is an avidity measure and can be captured within a LOINC term.

No response will be sent due to the age of the request.

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