Opened 8 years ago

Last modified 8 weeks ago

#135 assigned enhancement

Add unit AFU - Arbitrary Fluorescent Unit

Reported by: Lloyd McKenzie Owned by: Dan Vreeman
Priority: minor Milestone:
Component: help Keywords:
Cc:

Description

259k hits for "Arbitrary Fluorescent Unit" on google. Used when examining genetic sequences. A CDISC unit of measure.

Change History (4)

comment:1 Changed 8 years ago by Lloyd McKenzie

Type: questionenhancement

comment:2 Changed 7 years ago by Gunther Schadow

Hits on Google, we need a paper which establishes this unit not only to be mentioned internally in some experiment, but where a measurement expressed in these arbitrary fluorescence unit are actually exchanged, communicated.

comment:3 Changed 3 months ago by Brenée Mitchell

Component: help
Owner: set to Dan Vreeman
Status: newassigned

comment:4 Changed 8 weeks ago by Brenée Mitchell

Comment from Dan Vreeman:

Prior board member comment was the need for scientific supporting evidence that this unit was used/exchanged. A quick pubmed search and I could not find further information. This paper https://doi.org/10.1371/journal.pone.0199432 about bacterial fluorescence suggests that completely arbitrary (“a.u.”) or various normalized units against some control cell sample (e.g., RPU, ratiometric, REU) are used but characterizes and recommends an approach using independent calibrants. Given the lack of clarifying references, I recommend that we close this ticket as "insufficient evidence available" or something to that effect.

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